Antiemetic, anti-motion sustained release drug delivery system
OwnerAlan Drizen, Gary M. Nathinventors
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Abstract
This invention relates to a stable, sterilized, purified composition having a polymer matrix and a therapeutically effective amount of a drug, wherein the drug can be used to prevent or treat drug-induced, alcohol-induced, biologically-induced, trauma-induced or pain-induced nausea, vomiting, dizziness and other adverse effects arising from but not limited to motion sickness, cancer therapy, and pregnancy. In particular, the polymer matrix may be conformable to topical application on animal skin.
Claims48
A stable, sterilized, purified composition, comprising:
- a polymer matrix;
- and
- a therapeutically effective amount of a drug, wherein said drug is used to prevent or treat drug-induced, alcohol-induced, biologically-induced, trauma-induced or pain-induced nausea, vomiting, dizziness and other adverse effects arising from but not limited to motion sickness, cancer therapy, and pregnancy.
A dermal dressing, comprising:
- a polymer matrix containing a negatively charged polymer in combination with a nonionic polymer, wherein the polymer matrix is conformable to topical application on animal skin;
- and
- wherein said polymer matrix contains a therapeutically effective amount of a drug to prevent or treat drug-induced, alcohol-induced, biologically-induced, trauma-induced or pain-induced nausea, vomiting, dizziness and other adverse effects arising from but not limited to motion sickness, cancer therapy, and pregnancy.
A method for administering a drug to an animal, comprising the step of:
- applying a dermal dressing to animal skin, wherein the dermal dressing is comprised of:
- a polymer matrix containing a negatively charged polymer in combination with a nonionic polymer, wherein the polymer matrix is conformable to topical application on animal skin;
- and
- wherein said polymer matrix contains a therapeutically effective amount of a drug to prevent or treat drug-induced, alcohol-induced, biologically-induced, trauma-induced or pain-induced nausea, vomiting, dizziness and other adverse effects arising from but not limited to motion sickness, cancer therapy, and pregnancy.
A method for preventing or treating a condition in an animal comprising the steps of:
- applying a polymer matrix film onto the animal on an area to be treated, wherein the polymer matrix film contains a negatively charged polymer in combination with a nonionic polymer, and is formable, flexible and moveable;
- and
- securing said polymer matrix film onto the area to be treated with a dressing fixative.
A method for preventing or treating nausea in an animal for a sustained period of time, comprising the step of:
- applying to said animal a polymer matrix, comprising a negatively charged polymer and a nonionic polymer in combination with a therapeutically effective amount of a drug for preventing or treating nausea.
A method for preventing or treating dizziness in an animal, comprising the step of:
- applying to said animal a polymer matrix, comprising a negatively charged polymer and a nonionic polymer in combination with a therapeutically effective amount of a drug for preventing or treating dizziness.
A method for preventing or treating vomiting in an animal, comprising the step of:
- applying to said animal a polymer matrix, comprising a negatively charged polymer and a nonionic polymer in combination with a therapeutically effective amount of a drug for preventing or treating vomiting.
A method for preventing or treating pre-operative or post-operative vomiting, nausea or dizziness in an animal, comprising the step of:
- applying to said animal a polymer matrix, comprising a negatively charged polymer and a nonionic polymer in combination with a therapeutically effective dose of a drug for preventing or treating vomiting, nausea or dizziness in pre-operative or post-operative procedures.
A method for preventing or treating cancer in an animal, comprising the step of:
- applying to said animal a polymer matrix, comprising a negatively charged polymer and a nonionic polymer in combination with a therapeutically effective amount of a drug for preventing or treating cancer.
A method for preventing or treating alcohol related disorders or diseases in an animal, comprising the step of:
- applying to said animal a polymer matrix, comprising a negatively charged polymer and a nonionic polymer in combination with a therapeutically effective dose of a drug for preventing or treating alcohol-related disorders.
Dependencies are inferred from the claim text.