Pharmaceutical composition
AssigneeConnetics Australia Pty Ltd
InventorsTony Wai-Chiu So, Peter P. Deo, Russell J. Tait
Life of this patent
Estimating the term…
Abstract
A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an acid in an amount to completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; a solvent composition including at least two of water, a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols; wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight.
Claims25
A pharmaceutical composition for topical administration, including, as the pharmaceutically active component,
- at least 5% by weight, based on the total weight of the composition of a 5 piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof;
- an acid in an amount to substantially completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof a solvent composition including a solvent selected from water and/or a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols;
- wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight.
A method for the treatment of hair loss and related indications in humans, which method includes
- providing
- a pharmaceutical composition for topical administration, including, as the pharmaceutically active component,
- at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof;
- an acid in an amount to substantially completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof;
- a solvent composition including a solvent selected from water and/or a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols;
- wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight;
- and
- applying topically to the human scalp a therapeutically or prophylactically effective amount of the pharmaceutical composition.
Dependencies are inferred from the claim text.