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US 2002/0165582 A1Published application
Method and apparatus for delivering materials to the body
OwnerChristopher H. Porterinventor
Life of this patent
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Abstract
An apparatus, method and composition for embolization of a vascular site in a blood vessel. The composition is introduced via catheter to the vascular site and activated by an activator introduced by the catheter or external means. The composition polymerizes or precipitates in situ via the activation provided by the catheter or external means.
Claims43
A method comprising:
- delivering a prepolymer composition to a vascular site in a blood vessel;
- introducing an activator to said vascular site;
- wherein said introducing at least partially polymerizes said prepolymer composition in situ thereby embolizing said blood vessel.
An apparatus comprising:
- a catheter to deliver a prepolymer to a vascular site in a blood vessel
- wherein said prepolymer is adapted to at least partially polymerize in situ by introducing an activator thereby embolizing said blood vessel,
- wherein said catheter is adapted to at least partially adhere to said polymerized prepolymer.
A composition comprising:
- a prepolymer, wherein said prepolymer is adapted to at least partially polymerize in situ by introducing an activator thereby embolizing a vascular site in a blood vessel.
A composition comprising:
- a first material, said first material adapted to at least partially polymerize in situ thereby embolizing a blood vessel,
- a second material, said second material adapted to initiate said polymerization,
- wherein said first material is at least one form chosen from a solution, a gel, and a foam.
A composition comprising:
- a prepolymer adapted to at least partially polymerize in situ thereby embolizing a blood vessel,
- wherein said prepolymer has a temperature above said blood vessel, such that introducing said prepolymer to a vascular site of said blood vessel polymerizes said prepolymer.
A composition comprising:
- a prepolymer, and
- a radio opaque agent comprising at least one metal,
- whereby said agent absorbs electromagnetic radiation thereby heating said prepolymer to at least partially polymerize said prepolymer thereby embolizing a blood vessel.
An apparatus comprising:
- a catheter to deliver a prepolymer to a vascular site in a blood vessel;
- and
- a fiber opticwherein said fiber optic is detachably connected to said catheter,
- whereby said prepolymer is adapted to at least partially polymerize in situ by introducing light waves from said fiber optic.
1 more element
An apparatus comprising:
- a catheter;
- a heating element;
- and
- a temperature sensing element, wherein said temperature sensing element provides temperature feedback to avoid at least partially polymerizing a prepolymer delivered by said catheter.
1 more element
An apparatus comprising:
- a catheter comprising (i) an inner dissolved polymer stream, and (ii) an outer flush stream, wherein said flush steam is adapted to remove a solvent from said dissolved polymer to cause said dissolved polymer to precipitate.
A composition comprising:
- a liquid embolic solution;
- and
- fibers, said fibers are adapted to anchor said liquid embolic solution to a vascular site in a blood vessel.
An apparatus comprising:
- a catheter;
- and
- a detachable catheter tip, wherein said catheter tip can be detached by an operator through a mechanically activated or heat activated detachment link.
A composition comprising:
- a liquid embolic solution;
- and
- a blood-soluble gas, wherein said composition forms a foam for delivery of said liquid embolic solution to a vascular site in a blood vessel.
An apparatus comprising:
- a catheter comprising a first channel for delivery of a dissolved polymer to a vascular site in a blood vessel, and a second channel for delivery of a material adapted to accelerate precipitation of said dissolved polymer.
A method comprising:
- delivering a first material to a vascular site in a blood vessel to promote cell adhesion;
- delivering a second material to said vascular site to fill at least a portion of a volume of said vascular site;
- delivering a third material to said vascular site to protect said vascular site,
- whereby said second material fills said volume between said first material and said second material.
1 more element
Dependencies are inferred from the claim text.