US 2002/0165356 A1Published application

Zinc finger binding domains for nucleotide sequence ANN

AssigneeThe Scripps Research Institute

InventorsCarlos F. Barbas III, Birgit Dreier

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Abstract

Polypeptides that contain from 2 to 12 zinc finger-nucleotide binding regions that bind to nucleotide sequences of the formula (ANN)2-12 are provided. Polynucleotides that encode such polypeptides and methods of regulating gene expression with such polypeptides and polynucleotides are also provided.

Claims15

Dependent claims

A polypeptide comprising from 2 to 12 zinc finger-nucleotide binding peptides at least one of which peptides contains a nucleotide binding region having the sequence of any of SEQ ID NO:

7-70 and 107-112.

Dependencies are inferred from the claim text.

Facts

Application: 10/080,100Filed 21 Feb 2002
Priority: 21 Feb 2001
Published: 7 Nov 2002
Term ends: Not estimatedThe source records don’t support an estimate.

Classification6 codes

C12N 15/63
Recombinant DNA-technology: introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
C07K 14/00
Peptides having more than 20 amino acids
C12P 21/02
Preparation of peptides or proteins: having a known sequence of two or more amino acids, e.g. glutathione
C12N
Microorganisms or enzymes

Family

Application60/367,356Continuation in part · filed 21 Feb 2001
Application10/080,100Continuation in part · filed 21 Feb 2002
US 7,067,617 B2Related patent
US 2002/0165356 A1This patent

From the US filing history. Foreign family members aren’t listed.

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