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US 2002/0165351 A1Published application
Novel compounds
OwnerMahanandeeshwar Gattu, David Michalovich +4inventors
InventorsMahanandeeshwar Gattu, David Michalovich, Alastair Reith, Mark A. Scheideler, Ping Tsui, Paula F. Zaratin
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Abstract
R35 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing R35 polypeptides and polynucleotides in diagnostic assays.
Claims10
An isolated polypeptide selected from the group consisting of:
- (a) an isolated polypeptide encoded by a polynucleotide comprising the sequence of SEQ ID NO:1;
- (b) an isolated polypeptide comprising a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO:2;
- (c) an isolated polypeptide having at least 95% identity to the polypeptide sequence of SEQ ID NO:2;
- and
- (d) fragments and variants of such polypeptides in (a) to (e):
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An isolated polynucleotide selected from the group consisting of:
- (a) an isolated polynucleotide comprising a polynucleotide sequence having at least 95% identity to the polynucleotide sequence of SEQ ID NO:
- 1;
- (b) an isolated polynucleotide having at least 95% identity to the polynucleotide of SEQ ID NO:1;
- (c) an isolated polynucleotide comprising a polynucleotide sequence encoding a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO:2;
- (d) an isolated polynucleotide having a polynucleotide sequence encoding a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO:2;
- (e) an isolated polynucleotide with a nucleotide sequence of at least 100 nucleotides obtained by screening a library under stringent hybridization conditions with a labeled probe having the sequence of SEQ ID NO:
- 1 or a fragment thereof having at least 15 nucleotides;
- (f) a polynucleotide which is the RNA equivalent of a polynucleotide of (a) to (e);
- or a polynucleotide sequence complementary to said isolated polynucleotide and polynucleotides that are variants and fragments of the above mentioned polynucleotides or that are complementary to above mentioned polynucleotides, over the entire length thereof.
6 more elements
Dependencies are inferred from the claim text.