Human cytokine receptor
OwnerScott R. Presnell, Rolf E. Kuestner +1inventors
InventorsScott R. Presnell, Rolf E. Kuestner, Zeren Gao
Life of this patent
Estimating the term…
Abstract
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytorl8.”
Claims17
An isolated polypeptide, comprising an amino acid sequence selected from the group consisting of:
- (a) an amino acid sequence comprising amino acid residues 36 to 189 of SEQ ID NO:
- 2, (b) amino acid residues 1 to 189 of SEQ ID NO:
- 2, (c) amino acid residues 36 to 313 of SEQ ID NO:
- 2, (d) amino acid residues 336 to 753 of SEQ ID NO:
- 2, (e) amino acid residues 36 to 753 of SEQ ID NO:
- 2, (f) amino acid residues 1 to 753 of SEQ ID NO:
- 2, (g) amino acid resides 1 to 299 of SEQ ID NO:
- 8, (h) amino acid residues 36 to 299 of SEQ ID NO:
- 8, (i) amino acid residues 36 to 175 of SEQ ID NO:
- 8, (j) amino acid residues 1 to 300 of SEQ ID NO:
- 12, and (k) amino acid residues 36 to 300 of SEQ ID NO:
- 12.
An isolated nucleic acid molecule encoding a polypeptide that comprises an amino acid sequence selected from the group consisting of:
- (a) an amino acid sequence comprising amino acid residues 36 to 189 of SEQ ID NO:
- 2, (b) amino acid residues 1 to 189 of SEQ ID NO:
- 2, (c) amino acid residues 36 to 313 of SEQ ID NO:
- 2, (d) amino acid residues 336 to 753 of SEQ ID NO:
- 2, (e) amino acid residues 36 to 753 of SEQ ID NO:
- 2, (f) amino acid residues 1 to 753 of SEQ ID NO:
- 2, (g) amino acid resides 1 to 299 of SEQ ID NO:
- 8, (h) amino acid residues 36 to 299 of SEQ ID NO:
- 8, (i) amino acid residues 36 to 175 of SEQ ID NO:
- 8, (j) amino acid residues 1 to 300 of SEQ ID NO:
- 12, and (k) amino acid residues 36 to 300 of SEQ ID NO:
- 12.
An expression vector, comprising a nucleic acid molecule that encodes amino acid residues 36 to 313 of SEQ ID NO:
- 2, a transcription promoter, and a transcription terminator, wherein the promoter is operably linked with the nucleic acid molecule, and wherein the nucleic acid molecule is operably linked with the transcription terminator.
An antibody or antibody fragment that specifically binds with a polypeptide that has an amino acid sequence consisting of amino acid residues 1 to 189 of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.