Administration of sleep restorative agents
OwnerAndrew Holmaninventor
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Abstract
The present invention provides methods and compositions for increasing the efficacy of a therapeutic agent administered to a subject. A sleep restorative agent is co-administered to the subject along with the therapeutic agent, whereby the efficacy of the therapeutic agent is increased.
Claims39
A method for increasing the efficacy of a therapeutic agent administered to a subject having an autoimmune condition, comprising co-administering to the subject an effective amount of a sleep restorative agent or a pharmacologically acceptable addition salt thereof, and a therapeutic agent;
- whereby the efficacy of the therapeutic agent is increased.
A method for sparing an effective amount of a therapeutic agent administered to a subject having an autoimmune condition, comprising:
- co-administering to the subject the therapeutic agent and an effective amount of a sleep restorative agent, the sleep restorative agent improving sleep quality of the subject;
- whereby the sleep restorative agent spares the effective amount of the therapeutic agent.
A method for sparing an effective amount of a therapeutic agent administered to a subject having an autoimmune condition, comprising:
- co-administering to the subject the therapeutic agent and an effective amount of a sleep restorative agent, the sleep restorative agent reducing excessive sympathetic tone of the subject;
- whereby the sleep restorative agent spares the effective amount of the therapeutic agent.
A method for reducing a symptom in a subject in need of immunomodulatory therapy, comprising co-administering an effective amount of an immunomodulatory agent and an effective amount of a sleep restorative agent, the sleep restorative agent improving sleep quality of the subject;
- whereby the sleep restorative agent spares the effective amount of the immunomodulatory agent needed to reduce the symptom.
A composition for administration to a subject having an autoimmune disease, comprising:
- an effective amount of a sleep restorative agent;
- and
- and an effective amount of a therapeutic agent;
- the effective amount of the therapeutic agent spared by the sleep restorative agent.
Dependencies are inferred from the claim text.