Peptides and their use to ameliorate cell death
AssigneeCV Molecular Therapeutics, Inc.
InventorsGerald Krystal, Simon W. Rabkin
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Abstract
There is disclosed novel peptides, fragments or analogues thereof and polynucleotides encoding the same, obtained from streptokinase suitable for use in the amelioration of cell death and methods related thereto.
Claims23
A method of treating or preventing cell death in a warm-blooded animal, comprising administering to said animal a therapeutically effective amount of a peptide comprising the amino acid sequence Val-Asp-Val such that cell death is ameliorated.
A method of treating or preventing cell death in a warm-blooded animal, comprising administering to said animal a therapeutically effective amount of a streptokinase peptide that ameliorates cell death, or a derivative or analog thereof.
A pharmaceutical composition comprising a peptide capable of ameliorating cell death death, or a derivative or analog thereof, said peptide comprising the amino acid sequence Val-Asp-Val, wherein said peptide is in a suitable pharmaceutical carrier or diluent.
Dependencies are inferred from the claim text.