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US 2002/0165118 A1Published application
Hypotension
OwnerWalter J. Koch, Andrea D. Eckhartinventors
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Abstract
The present invention relates, in general, to hypotension and, in particular, to a novel therapeutic target for lowering blood pressure.
Claims6
A non-human transgenic animal that expresses GqI specifically in vascular smooth muscle cells thereof, and cells derived from said animal.
A method of screening a test compound for anti-hypertensive activity comprising determining the ability of said compound to inhibit intracellular Gq signaling in vascular smooth muscle cells.
Dependencies are inferred from the claim text.