Use of purinergic receptor modulators and related reagents
AssigneeSyntex (U.S.A.) Inc.
InventorsDebra Ann Cockayne, Anthony P.D.W. Ford, Quan-Ming Zhu, Wilhelm G. Lachnit, Annika B. Malmberg
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Abstract
The invention provides a method of treatment for an animal having a disease state associated with a genitourinary disorder with a purinergic receptor modulator. Also provided, is a transgenic animal having a disrupted purinergic receptor gene. The invention further provides for a method of screening using the transgenic animal as a positive control.
Claims20
A method of treating a subject having a disease state associated with a genitourinary or pain disorder comprising administering to the animal an effective amount of a purinoreceptor modulator.
A transgenic animal containing an altered allele for the gene that naturally encodes and expresses a functional P2X3 receptor subunit.
Dependencies are inferred from the claim text.