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US 2002/0164800 A1Published application
Retroviral vector
OwnerClayton A. Smith, Eli Gilboainventors
Life of this patent
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Abstract
The present invention relates, in general, to a retroviral vector and, in particular, to a Moloney murine leukemia virus-based retroviral vector. The invention further relates to methods of introducing genetic elements into cells, including mammalian cells, using such a vector.
Claims24
A retroviral vector comprising, 5′ to 3′ and in operable linkage, a 5′ long terminal repeat (LTR), a splice donor, a packaging sequence, a gag open reading frame (ORF) mutated to reduce translation of gag peptides, a splice acceptor, a start codon in frame with a DNA sequence and a 3′ LTR.
Dependencies are inferred from the claim text.