Micro organism cultivation device

Abstract

In the micro organism cultivation device of this invention, an implantable bio-artificial micro device, i.e., a cell apartment, is provided to cultivate cells or tissues. The cells or tissues to be cultivated include that secrete hormones such as islets of Langerhans. At both sides of the cell apartment, provided are microfluidic channels comprising dynamic micro-electric field array filters. The dynamic micro-electric field array filters comprise a plurality of electrodes distributed inside the microchannels. By periodically switching the polarity of the electrodes, microfluidic flows are generated in the microchannels. All inlet flows to the cell apartment are filtered by the immunoisolation of the micro-electric field array filters before entering into the cell apartment. The micro-electric field array filters provide a physical immune protection to the cells cultivated in the cell apartment against the immune system of the host. The microfluidic flows driven by the micro-electric field array accelerate the release of the hormones secreted by the cells cultivated in the cell

Dependencies are inferred from the claim text.