US 2002/0164692 A1Published application

Immune system-related polynucleotides, polypeptides, and antibodies

OwnerJian Ni, David Hilbert +8inventors

InventorsJian Ni, David Hilbert, Joseph J. Kenny, Paul A. Moore, Gil H. Choi, Daniel R. Soppet, Reinhard Ebner, Joachim R. Gruber, Gregory A. Endress, Steven M. Ruben

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Abstract

The present invention relates to novel human immune system-related polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human immune system-related polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human immune system-related polypeptides.

Claims22

Dependent claims

An isolated nucleic acid molecule comprising a polynucleotide selected from the group consisting of:

(a) the polynucleotide shown as SEQ ID NO:X or the polynucleotide encoded by a cDNA included in ATCC Deposit No:Z;
(b) a polynucleotide encoding a biologically active polypeptide fragment of SEQ ID NO:Y or a biologically active polypeptide fragment encoded by the cDNA sequence included in ATCC Deposit No:Z;
(c) a polynucleotide encoding a polypeptide epitope of SEQ ID NO:Y or a polypeptide epitope encoded by the cDNA sequence included in ATCC Deposit No:Z;
(d) a polynucleotide capable of hybridizing under stringent conditions to any one of the polynucleotides specified in (a)-(c), wherein said polynucleotide does not hybridize under stringent conditions to a nucleic acid molecule having a nucleotide sequence of only A residues or of only T residues.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 09/949,842Filed 12 Sep 2001
Priority: 8 Mar 2000
Published: 7 Nov 2002
Term ends: Not estimatedThe source records don’t support an estimate.

Classification15 codes

C07K 14/47
From vertebrates: from mammals
A61P 19/02
Drugs for skeletal disorders: for joint disorders, e.g. arthritis, arthrosis
A61P 25/00
Drugs for disorders of the nervous system
A61P 29/00
Non-central analgesic, antipyretic or antiinflammatory agents