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US 2002/0164657 A1Published application
Assays for assessing A beta-Tau aggregation
OwnerSatish K. Sharma, Kenneth B. Rankinventors
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Abstract
The present invention deals with the field of cell biology, more specifically the field of neuronal cell biology and neurodegenerative diseases. The invention provides for assays assessing Aβ-Tau aggregation
Claims20
A method for identifying agents that are inhibitors of tau-beta amyloid complex formation comprising:
- (a) contacting a tau protein derived polypeptide and an aggregated beta-amyloid peptide in the presence and absence of a test agent;
- and
- (b) determining the amount of tau-beta amyloid complex formed in the presence and absence of the test agent;
- and
- (c) comparing the amount of tau-beta amyloid complex formed in the presence of the test agent with the amount of tau-beta amyloid complex formed in the absence of the test agent wherein a test agent which decreases the amount of tau-beta amyloid complex formed is an inhibitor.
2 more elements
Dependencies are inferred from the claim text.