Topical composition for the treatment of psoriasis and related skin disorders
AssigneeBioDerm, Inc.
InventorLorraine Faxon Meisner
Life of this patent
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Abstract
Compositions and methods of use thereof for the treatment of psoriasis and related skin ailments are disclosed. The compositions include topical skin formulations of glucosamine in an emollient base such as moisturizing cream. In addition to glucosamine, the formulations may include keratolytic substances such as coal tar extract or salicylic acid. The formulations may also include glucosamine and antioxidant anti-inflammatory herbal extracts such as oleuropein and berberine in an emollient base.
Claims101
A topical skin preparation comprising glucosamine in an emollient base.
A formulation comprising glucosamine in an emollient base, wherein the formulation may be suitable for topical application on human skin, and further wherein the formulation at least partially suppresses, local to the area of topical application, the production of at least one cytokine that stimulates the proliferation of apoptosis-resistant keratinocytes.
A formulation suitable for topical application on mammalian skin, the formulation comprising glucosamine and extract from at least one herb, wherein the at least one herb extract elicits at least one of the following biological effects:
- anti-inflammatory, antioxidant, antibacterial, antimicrobial, anti-pruritic, anti-platelet adhesion, vasodilation or keratolysis.
A formulation suitable for topical application on mammalian skin, the formulation comprising:
- approximately in the range of 5-25% glucosamine by weight;
- approximately in the range of 1-10% berberine by weight;
- approximately in the range of 0.5-7.5% oleuropein by weight;
- and
- approximately in the range of 47.5-93.5% emollient by weight,
- whereby the formulation mitigates skin ailments local to the area of application.
A method for the treatment of skin ailments, the method comprising:
- providing a formulation, the formulation further comprising:
- approximately in the range of 5-25% glucosamine by weight;
- approximately in the range of 1-10% berberine by weight;
- approximately in the range of 0.5-7.5% oleuropein by weight;
- and
- approximately in the range of 47.5-93.5% emollient by weight, and topically applying the formulation to the affected skin.
A method for the treatment of skin ailments, the method comprising:
- providing a formulation, the formulation further comprising glucosamine and extract from at least one herb, wherein the at least one herb extract elicits at least one of the following biological effects:
- anti-inflammatory, antioxidant, antibacterial, antimicrobial, anti-pruritic, anti-platelet adhesion, vasodilation or keratolysis, and
- topically applying the formulation to the affected skin.
A method for the treatment of skin ailments, the method comprising:
- providing a formulation, the formulation further comprising glucosamine and at least one antioxidant anti-inflammatory in an emollient base;
- and
- topically applying the formulation to the affected skin.
Dependencies are inferred from the claim text.