Neoglycoproteins

A polyamide conjugate comprising either (a) a xenoantigenic group;

• or (b) a biologically active group and a macromolecular, macro- or microscopic entity;
• bound to a polyamide backbone,
• wherein the polyamide backbone comprises at least one structural element of formula I
• 36
• and in case (b) additionally at least one structural element of formula II
• 37
• in which
• each of A and A′, independently, is a trivalent bridging group;
• each of R1 and R1′, independently, is a direct bond or C1-C6alkylene;
• each of X1 and X1′, independently, is —C(O)O—, —C(O)NR—, —NR—, —S— or —O—;
• each of R2 and R2′, independently, is a direct bond or a bivalent bridging group;
• each of X2 and Xz, independently, is a direct bond or —O—or —NR—;
• wherein R is hydrogen, OH, C1-C12alkyl, C2-C12alkenyl, C3-C8cycloalkyl, C3-C8cycloalkenyl, C2-C7heterocycloalkyl, C2-C11heterocycloalkenyl, C6- or C10aryl, C5-C9heteroaryl, C7-C16aralkyl, C8-C16aralkenyl with C2-C6alkenylene and C6- or C10aryl, or di-C6- or C10aryl-C1-C6-alkyl;
• and
• each of Y and Y′, independently, is a direct bond or a bivalent bridging group;
• with the proviso that X1 or X1′ is not —NR—, —S— or —O— when R1 or R1′ is a direct bond.