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US 2002/0164334 A1Published application
Antibody-induced apoptosis
AssigneeAmgen Inc.
InventorsTsutomu Arakawa, Yoshiko Kita
Life of this patent
Estimating the term…
Abstract
Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The antibodies are used to “tag” Her2 overexpressing tumors for elimination by the host immune system. Also disclosed are hybridoma cell lines producing the antibodies, methods for treating cancer using the antibodies, and pharmaceutical compositions.
Claims18
An antibody or fragment thereof which induces apoptosis in cells expressing Her2.
An antibody produced by the hybridoma cell line ATCC No. ______.
Hyridoma cell line ATCC No. ______.
Dependencies are inferred from the claim text.