Process for purifying antibody
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsToyohide Shinkawa, Kazuhisa Uchida, Motoo Yamasaki, Emi Hosaka, Kenya Shitara
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Abstract
The present invention relates to a process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody; a medicament comprising, as an active ingredient, the antibody purified by the process; and a method for diagnosing or preventing various diseases, which comprises using a substance having an affinity to a carbohydrate binding to an antibody.
Claims21
A process for purifying an antibody having a desired property, which comprises using a substance having an affinity to a carbohydrate binding to the antibody.
A process for purifying an antibody having a carbohydrate structure to which bisecting N-acetylglucosamine is bound, which comprises using a column to which a wheat germ lectin or a Lens culinaris lectin E4 is immobilized.
A process for purifying an antibody having a high antibody-dependent cell-mediated cytotoxic activity, which comprises using a column to which a wheat germ lectin or a Lens culinaris lectin E4 is immobilized.
A process for purifying an antibody having a carbohydrate structure to which fucose is bound, which comprises using a column to which a Lens culinaris lectin is immobilized.
A process for purifying an antibody having a high antibody-dependent cell-mediated cytotoxic activity, which comprises using a column to which a Lens culinaris lectin is immobilized.
A process for purifying an antibody having a carbohydrate structure to which galactose is bound, which comprises using a carrier for hydrophobic chromatography.
A process for purifying an antibody having a high complement-dependent cytotoxic activity or antibody-dependent cell-mediated cytotoxic activity, which comprises using a carrier for hydrophobic chromatography.
A method for diagnosing various diseases, which comprises using a substance having an affinity to a carbohydrate binding to an antibody.
Dependencies are inferred from the claim text.