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AssigneeISTA Pharmaceuticals, Inc.
InventorsHAMPAR KARAGEOZIAN, VIKEN KARAGEOZIAN, MARIA C. KENNEY, JOSE L. G. FLORES, GABRIEL ARTURO CARPIO ARAGON, ANTHONY B. NESBURN
Estimating the term…
An enzymatic method is provided for treating ophthalmic disorders of the mammalian eye. Prevention of neovascularization and the increased rate of clearance from the vitreous of materials toxic to retina is accomplished by administering an amount of hyaluronidase effective to liquefy the vitreous humor of the treated eye without causing toxic damage to the eye. Liquefaction of the vitreous humor increases the rate of liquid exchange from the vitreal chamber. This increase in exchange removes those materials and conditions whose presence causes ophthalmological and retinal damage.
A method for inducing liquefaction of a vitreous humor to prevent a disorder of a mammalian eye comprising the step of contacting with said vitreous humor of said mammalian eye an amount of hyaluronidase effective to liquefy said vitreous humor whereby said disorder is prevented without causing toxic damage to said mammalian eye.
A method for treating a disorder of a mammalian eye comprising the step of:
The method of claim 24 wherein said vitreous humor is free of hemorrhagic blood that permits viewing of a retina of said mammalian eye.
The method of claim 24 wherein said contacting step is practiced in the absence of vitrectomy.
Dependencies are inferred from the claim text.