Back to results
US 2002/0161410 A1Published application
Apparatus and method for reversal of myocardial remodeling with electrical stimulation
AssigneeCardiac Pacemakers, Inc.
InventorsAndrew P. Kramer, Rodney W. Salo, Julio C. Spinelli, Bruce H. KenKnight
Life of this patent
Estimating the term…
Abstract
An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
Claims18
A method for cardiac pacing, comprising:
- delivering a stimulatory pulse to a ventricular pacing site in response to sensed cardiac activity and lapsed time intervals in accordance with a programmed pacing mode;
- and,
- wherein the pacing site is selected such that a stressed region of the ventricular myocardium is pre-excited relative to other regions in order to unload the stressed region and effect reversal of ventricular remodeling.
A cardiac rhythm management device, comprising:
- one or more ventricular sensing channels for sensing ventricular depolarizations and generating ventricular sense signals in accordance therewith;
- a plurality of stimulatory channels for delivering stimulation to one or more ventricular pacing sites;
- a controller for controlling the delivery of stimulatory pulses in accordance with a programmed pacing mode;
- and,
- wherein the controller is programmed to pace one or more pacing sites during a cardiac cycle by delivering pulses in a specified pulse output sequence such that a stressed region of the ventricular myocardium is excited before other regions.
2 more elements
Dependencies are inferred from the claim text.