Vaginal ring preparation and application
OwnerChen Hai Lin, Shao Hai Hao +2inventors
InventorsChen Hai Lin, Shao Hai Hao, Chen Jian Xing, Chen Liang Kang
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Abstract
A vaginal drug delivery device includes a tubular base of an inert rubber composition, a first layer having a thickness up to 3 mm composed of a mixture of a drug to delivered, at least one surfactant and at least one dispersing agent applied to said outer surface of the tubular base, and a second layer of silicone rubber having a thickness up to 1 mm encapsulating the first layer on the tubular base whereby said drug will diffuse through said second layer when the device is inserted into the vagina to treat the patient with the drug in the first layer.
Claims10
A vaginal drug delivery device comprising:
- a tubular base of an inert rubber composition having an outer surface;
- a first layer having a thickness from 0.3 mm to 3 mm applied to said outer surface of said tubular base, said first layer comprising a mixture of a drug to delivered, at least one surfactant and at least one dispersing agent;
- and
- a second layer of silicone rubber having a thickness from 0.02 to 1 mm encapsulating said first layer on said tubular base whereby said drug will diffuse through said second layer when the device is inserted into the vagina to treat a patient with said drug.
A method of vaginal delivery of drugs through gradual release comprising the steps of:
- forming a inert base of a rubber composition;
- applying a first layer on said inert base composed of a mixture of a drug to be administered, a surfactant and a dispersing agent, said first layer have a thickness less than 3 mm;
- encapsulating said first layer with a second layer of silicone rubber, said second layer having a thickness of less than 1 mm;
- and
- inserting said device into the vaginal cavity of a patient to be treated with the drug.
Dependencies are inferred from the claim text.