Transcranial examination of the brain

A method of transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising

• (a) introducing electromagnetic radiation of a selected wavelength into the brain at an input port placed at a selected location on the exterior of the head,
• (b) detecting, at a detection port placed at a selected location on the exterior of the head, radiation of said selected wavelength that has migrated in the brain,
• (c) causing stimulation of a brain activity while introducing said radiation at said input port and while detecting radiation of said detection port,
• (d) processing signals of said detected radiation that has migrated in the brain to create processed data, and
• (e) determining a characteristic of said brain activity by correlating said processed data with said caused stimulation of said brain activity.

A method of transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising

• (a) introducing electromagnetic radiation of a selected wavelength into the brain simultaneously at a first input port and at a second input port, said first input port and said second input port being placed at a first selected location and a second selected location on the exterior of the head, respectively,
• (b) detecting simultaneously, at a first detection port placed at a selected location on the exterior of the head, radiation that has migrated in the brain from said first input port to said first detection port and, at a second detection port placed at second selected location on the exterior of the head, radiation that has migrated in the brain from said second input port to said second detection port,
• (c) causing stimulation of a brain activity while introducing said radiation at said first and second input ports and while detecting radiation at said first and second detection ports,
• (d) processing signals of said detected radiation that has migrated in the brain to create processed data, and
• (e) determining a characteristic of said brain activity by correlating said processed data to said caused stimulation of said brain activity.

A cognition spectrophotometer system for transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising

• (a) a light source adapted to introduce electromagnetic radiation of a selected wavelength into the brain at an input port placed at a selected location on the exterior of the head,
• (b) a detector adapted to detect, at a detection port placed at a selected location on the exterior of the head, radiation of said selected wavelength that has migrated in the brain,
• (c) stimulation means adapted to cause stimulation of a brain activity while introducing said selected wavelength and while detecting radiation at said detection port,
• (d) processing means adapted to process signals of said detected radiation that has migrated in the brain to create processed data, and
• (e) evaluation means adapted to determine a characteristic of said brain activity by correlating said processed data with said caused stimulation of said brain activity.

A cognition spectrophotometer system for transcranial examination of brain activity by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising

• (a) a first light source and a second light source adapted to introduce electromagnetic radiation of a selected wavelength into the brain simultaneously at a first input port and at a second input port, said first input port and said second input port being placed at a first selected location and a second selected location on the exterior of the head, respectively,
• (b) a first detector and a second detector adapted to detect simultaneously, at a first detection port placed at a selected location on the exterior of the head, radiation that has migrated in the brain from said first input port to said first detection port and, at a second detection port placed at second selected location on the exterior of the head, radiation that has migrated in the brain from said second input port to said second detection port,
• (c) stimulation means adapted to cause stimulation of a brain activity while introducing said radiation at said first and second input ports and while detecting radiation at said first and second detection ports,
• (d) processing means adapted to process signals of said detected radiation that has migrated in the brain to create processed data, and
• (e) evaluation means adapted to determine a characteristic of said brain activity by correlating said processed data to said caused stimulation of said brain activity.

A method of transcranial examination of a brain tissue by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the brain comprising

• (a) introducing electromagnetic radiation of a selected wavelength into the brain simultaneously at a first input port and at a second input port, said first input port and said second input port being placed at a first selected location and a second selected location on the exterior of the head, respectively,
• (b) detecting simultaneously, at a first detection port placed at a selected location on the exterior of the head, radiation that has migrated in the brain from said first input port to said first detection port and, at a second detection port placed at second selected location on the exterior of the head, radiation that has migrated in the brain from said second input port to said second detection port,
• (c) processing signals of said radiation detected at said first and second detection port that have migrated in the brain to create first and second processed data, respectively, and
• (d) determining a selected property of said brain tissue by correlating said processed first and second data.

A method of in vivo examination of a tissue of a human by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in said tissue comprising

• (a) introducing electromagnetic radiation of a selected wavelength into the tissue at a first input port placed at a selected location on said human,
• (b) detecting, at a first detection port placed at a selected location on said human, radiation of said selected wavelength that has migrated in the first localized tissue of interest from said first input port to said first detection port,
• (c) introducing electromagnetic radiation of said selected wavelength into the tissue at a second input port placed at a second selected location on said human,
• (d) detecting, at a second detection port placed at a selected location on said human, radiation of said selected wavelength that has migrated in the second localized tissue of interest from said second input port to said second detection port, said first localized tissue of interest having normal physiological properties, said second localized tissue of interest being examined for pathophysiological changes,
• (e) processing signals of said detected radiation that has migrated in said first and second localized tissues of interest to create first and second processed data, and
• (f) determining pathophysiological changes in said second localized tissue of interest by correlating both said first and said second processed data.