Rattlesnake venom gland proteins
OwnerPaul O. Sheppard, Paul D. Bishopinventors
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Abstract
Due to their biological activity, snake venom proteins have found a variety of uses in therapeutic and diagnostic applications. Zsnk proteins are C-type lectin proteins expressed in the venom gland of the pigmy rattlesnake (Sistrurus miliarius). This species is a member of the Viperidae, a snake family known for producing venom that affects the blood coagulation and platelet aggregation system.
Claims13
An isolated polypeptide, comprising an amino acid sequence selected from the group consisting of:
- the amino acid sequence of amino acid residues 21 to 140 of SEQ ID NO:2, the amino acid sequence of amino acid residues 25 to 150 of SEQ ID NO:5, the amino acid sequence of amino acid residues 13 to 138 of SEQ ID NO:8, and the amino acid sequence of amino acid residues 27 to 152 of SEQ ID NO:11.
An isolated nucleic acid molecule, wherein the nucleic acid molecule encodes a polypeptide comprising an amino acid sequence selected from the group consisting of:
- the amino acid sequence of amino acid residues 20 to 151 of SEQ ID NO:2, the amino acid sequence of amino acid residues 24 to 152 of SEQ ID NO:5, the amino acid sequence of amino acid residues 10 to 144 of SEQ ID NO:8, and the amino acid sequence of amino acid residues 24 to 158 of SEQ ID NO:11.
Dependencies are inferred from the claim text.