Back to results
US 2002/0161043 A1Published application
Sulphoxybenzamides
AssigneeBoehringer Ingelheim Pharma GmbH & Co. KG
InventorsRalf Anderskewitz, Kurt Schromm, Franz Birke, Hans Michael Jennewein
Life of this patent
Estimating the term…
Abstract
The present invention relates to new sulphoxybenzamides of general formula I, processes for preparing them as well as their use as medicaments. 1
Claims13
A compound of formula I
- 9
- wherein
- Z0 denotes a group selected from the formulae —X1—(CH2)r—X2— and —CR4R5—,
- A1 and A2 independently of one another each denote a 1,4-phenylene- or 1,3-phenylene group, each optionally substituted by one or more halogen atoms, C1—C8-alkyl groups, C2—C8-alkenyl groups, C1—C8-haloalkyl groups or C1—C8-alkoxy groups,
- Z1 and Z2 independently of one another each denote a group of formula —X3—(CH2)s—X4— or a single bond,
- R1 denotes hydrogen, hydroxy, —COO—C1—C8-alkyl or —COO—C1—C4-alkyl-phenyl, wherein said phenyl group may be substituted by C1—C4-alkyl or C1—C4-alkoxy,
- R2 and R3 independently of one another each denote a hydrogen or halogen atom, or a C1—C8-alkyl, C1—C8-haloalkyl, C1—C8-alkoxy, aryl, aryloxy or aralkyl group,
- R4 and R5 independently of one another each denote hydrogen or C1—C4-alkyl,
- X1 and X2 independently of one another each denote —O, —S, —NH— or a single bond,
- X3 and X4 independently of one another each denote —O, —S, —NH— or a single bond,
- m and n independently of one another each denote 0 or 1, and
- r and s independently of one another denote an integer from 1 to 8,
- optionally in the form of a tautomer, racemate, enantiomer, diastereomer and mixtures thereof, or a pharmacologically acceptable salt thereof.
10 more elements
A compound of formula IA
- 10
A compound of formula IB
- 11
Dependencies are inferred from the claim text.