Nitric oxide donor composition and method for treatment of anal disorders
AssigneeCellegy Pharmaceuticals, Inc.
InventorStephen R. Gorfine
Life of this patent
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Abstract
A pharmaceutical composition contains a nitric oxide donor and advantageously an optional corticosteroid and/or topical anesthetic. The composition is useful in a method for treating anal disorders such as anal fissure, anal ulcer, hemorrhoidal disease, levator spasm, and so forth, by topical application to or proximate the affected area.
Claims36
A pharmaceutical composition useful for topical treatment of an anal disease, said composition comprising an organic nitric oxide donor in combination with a carrier, in a form selected from the group consisting of a powder, an aerosol, a liquid to include a thickened liquid, an ointment and a suppository;
- wherein if the organic nitric oxide donor is only nitroglycerin and the composition is a soft paraffin or petroleum based ointment then the nitroglycerin is present in an amount excluding 2.0% by weight.
A pharmaceutical composition useful for treating anal disease comprising an organic nitric oxide donor in combination with a corticosteroid and a pharmaceutically acceptable topical carrier.
A pharmaceutical composition useful for treating anal disease comprising an organic nitric oxide donor in combination with a topical anesthetic and a carrier.
A method for treating an anal disease comprising contacting an appropriate anal area with an effective amount of nitric oxide.
Dependencies are inferred from the claim text.