Method of treating diseases using 6-amino EM-12
OwnerRobert D'Amatoinventor
Life of this patent
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Abstract
The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
Claims139
A method of treating an eye condition in a human, or an animal, comprising administering to the human, or the animal, a composition comprising 6-amino EM-12 having the formula
- 19
- or an analog, hydrolysis product, metabolite, or precursor thereof in an amount effective to treat the eye condition.
A method of treating an inflammatory or immune mediated disease in a human, or an animal, comprising administering to the human, or the animal, a composition comprising 6-amino EM-12 having the formula
- 20
- or an analog, hydrolysis product, metabolite, or precursor thereof in an amount effective to treat the inflammatory or immune mediated disease.
A method of treating an infectious disease in a human, or an animal, comprising administering to the human, or the animal, a composition comprising 6-amino EM-12 having the formula
- 21
- or an analog, hydrolysis product, metabolite, or precursor thereof in an amount effective to treat the infectious disease.
A method of treating a cancerous disease in a human, or an animal, comprising administering to the human, or the animal, a composition comprising 6-amino EM-12 having the formula
- 22
- or an analog, hydrolysis product, metabolite, or precursor thereof in an amount effective to treat the cancerous disease.
The method of 83, wherein the cancerous disease is rhabdomyosarcoma.
A method of treating a blood or blood vessel disease in a human, or an animal, comprising administering to the human, or the animal, a composition comprising 6-amino EM-12 having the formula
- 23
- or an analog, hydrolysis product, metabolite, or precursor thereof in an amount effective to treat the blood or blood vessel disease.
A method of treating a skin condition in a human, or an animal, comprising administering to the human, or the animal, a composition comprising 6-amino EM-12 having the formula
- 24
- or an analog, hydrolysis product, metabolite, or precursor thereof in an amount effective to treat the skin condition.
Dependencies are inferred from the claim text.