Method of local anesthesia and analgesia
AssigneeWex Medical Intrumentation Co., LTD.
InventorsYuling Liu, Wenjuan Yin
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Abstract
The present invention relates to a method of obtaining local anesthesia and analgesia to the nerve tissue region of a mammal by administration of an effective dose of sodium channel blocking compounds, including tetrodotoxin and/or saxitoxin and derivatives thereof, in a pharmaceutically suitable vehicle.
Claims15
A method of producing local analgesia or anesthesia in a nerve tissue region of a mammal experiencing pain caused by damage to or stimulation of a nerve tissue, comprising locally administering to the nerve tissue region of the mammal an anesthetically or analgesically effective dose of a pharmaceutical composition comprising a compound that binds to the SS1 or SS2 subunit of a sodium channel and a pharmaceutically suitable vehicle;
- wherein the nerve tissue region comprises:
- (i)the peribulbar nerve and its distribution or a part thereof;
- (ii) the retrobulbar nerve and its distribution or a part thereof;
- (iii) the whole or a part of cranial nerve III, IV or V and the distribution thereof;
- (iv) a ciliary ganglion and the whole or a part of the distribution thereof.
Dependencies are inferred from the claim text.