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OwnerGerald Kleymann, Rudiger Fischer +13inventors
InventorsGerald Kleymann, Rudiger Fischer, Martin Hendrix, Guy Hewlett, Veniamin Pevzner, Ulrich Betz, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Udo Schneider, Olaf Weber, Kerstin Henninger, Axel Jensen, Jorg Keldenich, Judith Baumeister
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The present invention relates to inhibitors of the viral helicase-primase enzyme complex with anti-herpes activity, and to medicaments containing these compounds in suitable formulation. The invention further describes a method for identifying substances with antiviral activity in order to treat herpes infections in humans and animals.
Medicament containing uncompetitive inhibitors of the herpes helicase-primase.
Method for identifying compounds with anti-herpes activity, characterized in that the compounds are tested for their ability to inhibit the enzymatic activity of helicase-primase, and those compounds which on competitively inhibit the helicase-primase enzyme complex are selected.
Dependencies are inferred from the claim text.