Enzyme containing granule
AssigneeNovozymes A/S
InventorErik Kjaer Markussen
Life of this patent
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Abstract
This invention relates to an enzyme containing granular composition comprising: a) an enzyme containing core and b) a protective substantially continuous layer or coating encapsulating the core comprising at least 60% of a water soluble compound, having a molecular weight below 500 grams per mole, a pH below 11 and a constant humidity at 20° C. of more than 81%. The invention provides an improved stability of enzymes upon storage.
Claims24
An enzyme containing granule comprising:
- a) an enzyme containing core and
- b) a protective substantially continuous layer or coating encapsulating the core comprising at least 60% of a water soluble compound, having a molecular weight below 500 grams per mole, a pH below 11 and a constant humidity at 20° C. of more than 81%.
The granule according to claim 1, wherein said water soluble compound has a molecular weight between 30-500 g/mole.
The granule according to any preceding claim, wherein said is water soluble compound has a solubility of at least 0.1 gram per 100 gram water.
The granule according to any preceding claim, wherein said water soluble compound has a solubility of at least 10 gram per 100 gram water.
The granule according to any preceding claim, wherein said water soluble compound has constant humidity at 20° C. of more than 90%.
The granule according to any preceding claim, wherein said core is a non absorbing core.
The granule according to claim 1, wherein said salt is selected from the group consisting of alkali or earth alkali metal ion salt of sulfate, sulfite, phosphate, phosphonate, nitrate, chloride, carbonate and simple organic acids.
The granule according to claim 1, wherein said salt is selected from the group consisting of Na2HPO4, Na3PO4, (NH4)H2PO4, KH2PO4, Na2SO4, K2SO4, KHSO4, ZnSO4 and sodium citrate.
The granule according to any preceding claim, wherein said coating further comprises one or more protective agents capable of inactivating components hostile to the enzyme entering the granule from a surrounding matrix.
The granule according to any preceding claim, wherein said coating constitutes 1-75% w/w of the coated granule.
The granule according any preceding claim, wherein said enzyme containing core comprises a particulate carrier and an enzyme containing layer.
The granule according to any preceding claim, wherein said enzyme is selected from the group consisting of oxidoreductases (EC 1.-.-.- ), transferases (EC 2-.-.-), hydrolases (EC 3.-.-.-), lyases (EC 4.-.-.-), isomerases (EC 5.-.-.-) and ligases (EC 6.-.-.-).
The granule according to any preceding claim further comprising an additional coating.
Dependencies are inferred from the claim text.