Method and probe set for detecting cancer
AssigneesMayo Foundation for Medical Education and Research, Vysis, Inc.
InventorsKevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
Life of this patent
Estimating the term…
Abstract
Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
Claims25
A method of screening for cancer in a subject comprising:
- (a) hybridizing a set of chromosomal probes to a biological sample from said subject;
- (b) selecting cells from said biological sample;
- (c) determining the presence or absence of aneusomic cells in said selected cells;
- (d) correlating presence of aneusomic cells in the selected cells with cancer in said subject.
A set of chromosomal probes, said set comprising centromeric probes to chromosomes 3, 7, and 17.
A kit for detecting cancer, said kit comprising a set of chromosomal probes, wherein said set comprises centromeric probes to chromosomes 3, 7, and 17.
Dependencies are inferred from the claim text.