Health food useful for preventing liver and biliary dysfunctions containing an alkanoyl l-carnitine and silybum marianum extract
AssigneeSigma-Tau HealthScience S.p.A.
InventorPietro Pola
Life of this patent
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Abstract
A health food/dietary supplement is disclosed endowed with a protective action on liver function against exogenous and endogenous hepatotoxic agents the characterizing components of which are isovaleryl L-carnitine and/or propionyl L-carnitine and an extract of Silybum marianum (milk thistle) standardised to at least 70% by weight of silymarin.
Claims14
A food/dietary supplement which comprises the following characterizing ingredients:
- (a) an alkanoyl L-carnitine selected from the group comprising isovaleryl L-carnitine, propionyl L-carnitine or a pharmacologically acceptable salts thereof or mixtures thereof;
- and
- (b) an extract of silybum marianum standardized to at least 70% by weight of silymarin.
The supplement of anyone of the preceding claims which further comprises vitamins, sugars, coenzymes, mineral substances, aminoacids, peptides and antioxidants.
The supplement of any of the preceding claims wherein the pharmacologically acceptable salt is selected from the group comprising:
- chloride;
- bromide;
- iodide;
- aspartate, acid aspartate;
- citrate, acid citrate;
- tartrate;
- phosphate, acid phosphate;
- fumarate, acid fumarate;
- glycerophosphate;
- glucose phosphate;
- lactate;
- maleate, acid maleate;
- mucate;
- orotate;
- oxalate;
- acid oxalate;
- sulphate, acid sulphate;
- trichloroacetate;
- trifluoroacetate and methane sulphonate.
The supplement of any of the preceding claims having protective action on liver function and integrity against lesions induced by exogenous and endogenous hepatotoxic agents.
The supplement of any of the preceding claims manufactured in solid or liquid form.
The supplement of any of the preceding claim in the form of tablets, capsules, lozenges, pills, granulates, syrups, herb teas, vials or drops.
The supplement of any of the preceding claims wherein the weight ratio of components (a):(b):(c) ranges from 1:0.1:1 to 1:1:2.
A method for preventing the damages induced by exposure to exogenous and endogenous hepatotoxic agents and exerting a protective action on liver function and integrity which comprises administering to an individual in need thereof a combination composition comprising the following ingredients:
- (a) an alkanoyl L-carnitine selected from the group comprising isovaleryl L-carnitine, propionyl L-carnitine or a pharmacologically acceptable salts thereof or mixtures thereof;
- and
- (b) an extract of silybum marianum standardized to at least 70% by weight of silymarin.
Dependencies are inferred from the claim text.