Chemokine receptor able to bind to MCP-1, MIP-1 alpha and/or rantes and its uses
AssigneeGlaxo Group Limited
InventorsTimothy N.C. Wells, Christine A. Power
Life of this patent
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Abstract
A chemokine receptor binds to MCP-1, MIP-1α and/or RANTES. It can be used in screening for agents which act as antagonists to MCP-1, MIP-1α and/or RANTES. Such agents may be useful in treating various disorders, including allergies, atheromas and diseases mediated by viruses. They may also be useful in preventing graft rejection and in protecting stem cells from potentially damaging effects of chemotherapy.
Claims13
A method of screening for an agent useful in therapy which comprises use of a polypeptide comprising the amino acid sequence shown in SEQ ID NO:6 or SEQ ID NO:20.
A method of screening for an agent useful in therapy which comprises use of a polypeptide having the amino acid sequence shown in SEQ ID NO:20.
Dependencies are inferred from the claim text.