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US 2002/0159952 A1Published application
Novel acoustically active drug delivery systems
OwnerEvan C. Ungerinventor
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OwnerEvan C. Ungerinventor
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The present invention is directed to targeted therapeutic delivery systems comprising a gas or gaseous precursor filled microsphere wherein said gas or gaseous precursor filled microsphere comprises an oil, a surfactant, and a therapeutic compound. Methods of preparing the targeted therapeutic delivery systems are also embodied by the present invention which comprise processing a solution comprising an oil and a surfactant in the presence of a gaseous precursor, at a temperature below the gel to liquid crystalline phase transition temperature of the surfactant to form gas or gaseous precursor filled microsphere, and adding to said microspheres a therapeutic compound resulting in a targeted therapeutic delivery system, wherein said processing is selected from the group consisting of controlled agitation, controlled drying, and a combination thereof.
A targeted therapeutic delivery system comprising a gas or gaseous precursor filled microsphere wherein said gas or gaseous precursor filled microsphere comprises an oil, a surfactant, and a therapeutic compound.
A method of preparing a targeted therapeutic delivery system comprising gas or gaseous precursor filled microspheres said method comprising the steps of processing a solution comprising an oil and a surfactant in the presence of a gaseous precursor, and adding to said microspheres a therapeutic compound, wherein said processing is selected from the group consisting of controlled agitation, controlled drying, and a combination thereof.
A method for the controlled delivery of a targeted therapeutic delivery system comprising:
Dependencies are inferred from the claim text.