Biologically active protein folding intermediates
AssigneeUniversity of Medicine and Dentistry of New Jersey
InventorsMasayori Inouye, Ujwal Shinde, Xuan Fu
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Abstract
This invention provides biologically active protein folding intermediates and methods of making and using the same.
Claims13
A method for preparing a biologically active intermediate of a folding protein comprising contacting an intermediate of a folding protein with an effective amount of a substrate or reducing agent.
A biologically active intermediate prepared by contacting an intermediate of a folding protein with an effective amount of a substrate or reducing agent.
A drug design assay comprising assessing a drug candidate's ability to stabilize or prevent formation of a biologically active intermediate of a folding protein.
Dependencies are inferred from the claim text.