Demineralized bone-derived implants
AssigneeSynthes USA, LLC
InventorsMichael L. Boyer II, David C. Paul, Christopher M. Angelucci
Life of this patent
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Abstract
Selectively demineralized bone-derived implants are provided. In one embodiment, a bone sheet for implantation includes a demineralized field surrounding mineralized regions. In another embodiment, a bone defect filler includes a demineralized cancellous bone section in a first geometry. The first geometry is compressible and dryable to a second geometry smaller than the first geometry, and the second geometry is expandable and rehydratable to a third geometry larger than the second geometry.
Claims24
A bone sheet for implantation, the sheet comprising an at least partially demineralized field substantially surrounding at least one mineralized region.
A method of forming a flexible bone sheet comprising:
- providing a sheet of cortical bone;
- creating at least one hole in the cortical sheet which is configured and dimensioned to receive a fastener;
- masking the cortical sheet proximate the at least one hole to create a masked region surrounding the at least one hole;
- and
- applying demineralizing agents to the cortical sheet around the masked region.
A sheet formed of bone comprising two or more strips of bone each having a bone grain orientation, wherein the bone grain orientation of at least one strip is disposed transverse to the grain orientation of another strip.
Dependencies are inferred from the claim text.