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AssigneeCouncil of Scientific and Industrial Research
InventorsSubhash Prataprao Chavan, Subhash Krishnaji Kamat, Latha Sivadasan, Kamalam Balakrishnan, Dushant Anandrao Khobragade, Ravindranathan Thottapillil, Mukund Keshao Gurjar, Uttam Ramrao Kalkote
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A process for the preparation of 1-[(cyano) aryl methyl] cyclohexanol of the general formula 1 (1a-d) by reacting cyclohexanone with the carbanions of an aryl acetonitrile of the general formula 3 (3a-d), 1 a) R1=H, R2=H b) R1=OMe R2=H c) R1=OMe R2=OMe d) R1=OMe R2=cyclopentyloxy using a base, isolating the compound of formula I and purifying the compound of formula 1a-d by crystallisation is disclosed.
A process for the preparation of 1-[(cyano) aryl methyl] cyclohexanol of the general formula 1 (1a-d), by reacting cyclohexanone with the carbanions of an aryl acetonitrile of the general formula 3 (3a-d),
10 A process as claimed in claim 1 wherein the base is used in a catalytic amount.
Dependencies are inferred from the claim text.