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US 2002/0120136 A1Published application
Method of preparing cephalosporins using 4-hydroxyphenylglycine derivatives
OwnerGwan-Sun Lee, Jae-Heon Lee +5inventors
InventorsGwan-Sun Lee, Jae-Heon Lee, Young-Kil Chang, Hong-Sun Kim, Chul-Hyun Park, Gha-Seung Park, Cheol-Kyung Kim
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Abstract
High purity cephalosporin compound can be easily prepared in a high yield by a process comprising the steps of: reacting a cephem compound with a 4-hydroxyphenylglycine derivative.
Claims23
A method of preparing a compound of formula (I) which comprises reacting a cephem compound of formula (II) with a 4-hydroxyphenylglycine derivative of formula (III) or formula (IV):
- 6
- wherein R1 is hydrogen or an amino protecting group,
- R2 is hydrogen or a carboxy protecting group, and
- 7
- .
2 more elements
Dependencies are inferred from the claim text.