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US 2002/0120131 A1Published application
Production of cyclodextrin complexes
AssigneeCerestar Holding B.V.
InventorZhihong Helena Qi
Life of this patent
Estimating the term…
Abstract
The process entails increasing the concentration of cyclodextrin to 15% (w/w) and above to form complexes through a precipitation process in order to increase the yield of complexes, increase the amount of guest complexed, and decrease the particle size of the complex.
Claims12
A process for increasing the yield of a complex of cyclodextrin and guest comprising the steps of:
- (a) forming a solution of cyclodextrin and guest molecule in a solvent wherein the cyclodextrin is present at a concentration of about 15% (w/w) or above, and said solution has a molecular ratio of cyclodextrin to guest of about 1:1 to about 10:1;
- (b) mixing the solution to allow a complex to form as a precipitate;
- and
- (c) separating said precipitate from said solution to recover said complex.
1 more element
A process for increasing the amount of guest complexed with cyclodextrin comprising the steps of:
- (a) forming a solution of cyclodextrin and guest molecule in a solvent wherein the cyclodextrin is present at a concentration of about 15% (w/w) or above, and said solution has a molecular ratio of cyclodextrin to guest of about 1:1 to about 10:1;
- (b) mixing the solution to allow a complex to form as a precipitate;
- and
- (c) separating said precipitate from said solution to recover said complex.
1 more element
A process for decreasing the size of guest complexed with cyclodextrin comprising the steps of:
- (a) forming a solution of cyclodextrin and guest molecule in a solvent wherein the cyclodextrin is present at a concentration of about 15% (w/w) or above, and said solution has a molecular ratio of cyclodextrin to guest of about 1:1 to about 10:1;
- (b) mixing the solution to allow a complex to form as a precipitate;
- and
- (c) separating said precipitate from said solution to recover said complex.
1 more element
Dependencies are inferred from the claim text.