Lymphoma associated molecules and uses therefor
AssigneeDana-Farber Cancer Institute, Inc.
InventorsMargaret A. Shipp, Ricardo Aguiar, Liqun Gu, Kunihiko Takeyama
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AssigneeDana-Farber Cancer Institute, Inc.
InventorsMargaret A. Shipp, Ricardo Aguiar, Liqun Gu, Kunihiko Takeyama
Estimating the term…
The invention provides isolated nucleic acids molecules, designated BBAP nucleic acid molecules, which encode proteins that interact with or bind to BAL molecules, which are differentially expressed in non-Hodgkin's lymphoma. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing BBAP nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a BBAP gene has been introduced or disrupted. The invention still further provides isolated BBAP proteins, fusion proteins, antigenic peptides and anti-BBAP antibodies. Diagnostic methods using compositions of the invention are also provided.
An isolated nucleic acid molecule selected from the group consisting of:
An isolated nucleic acid molecule which encodes a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
An isolated nucleic acid molecule which encodes a naturally occurring allelic variant of a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:
An isolated nucleic acid molecule selected from the group consisting of:
An isolated polypeptide selected from the group consisting of:
Dependencies are inferred from the claim text.