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US 2002/0120015 A1Published application
Novel microemulsion and micelle systems for solubilizing drugs
AssigneeUniversity of Florida
InventorsDonn M. Dennis, Nikolaus Gravenstein, Jerome H. Modell, Timothy E. Morey, Dinesh Shah
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Abstract
A microemulsion delivery system for water insoluble or sparingly water soluble drugs that comprises a long polymer chain surfactant component and a short fatty acid surfactant component, with the amount of each being selected to provide stable microemulsion or micellar systems.
Claims22
A microemulsion drug composition comprising:
- microemulsion oil droplets of a drug;
- said microemulsion size droplets being emulsified with an emulsifier combination;
- said emulsifier combination comprising a long chain polymer surfactant component and a short chain fatty acid surfactant component, the amounts of each component being selected to provide thermodynamically stable microemulsion droplets.
A method of controlling drug delivery and transfer rate of drugs comprising:
- preparing microdroplets of the drug with an emulsifier combination of a long chain polymer surfactant component, and a short chain fatty acid surfactant component, the amounts of each being selected to provide thermodynamically stable microemulsion droplets and to control delivery and transfer rate as desired.
Dependencies are inferred from the claim text.