Retinoic acid receptor antagonists as promoters of angiogenesis
AssigneeBristol-Myers Squibb Company
InventorsVioletta Iotzova, Peter Reczek
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Abstract
Methods and compositions for treating various disorders by administering a therapeutically effective amount of a retinoic acid receptor antagonist alone or in combination or in conjunction with other therapeutic agents to promote angiogenesis are provided. Also provided are methods for obtaining additional retinoic acid receptor antagonists for use as therapeutic agents to promote angiogenesis.
Claims27
A method of promoting angiogenesis in a mammal comprising administering to the mammal an effective amount of a retinoic acid receptor antagonist.
The use of a retinoic acid receptor antagonist in the treatment of pulmonary disease.
The use of a retinoic acid receptor antagonist in the treatment of cardiovascular disease.
The use of a retinoic acid receptor antagonist in the treatment of bone fracture.
Dependencies are inferred from the claim text.