Nimesulide gel systems for topical use
OwnerStefano Bader, Enrique Hausermann +1inventors
InventorsSTEFANO BADER, ENRIQUE HAUSERMANN, TIZIANA MONTI
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Abstract
The present invention relates to nimesulide topical formulations comprising a carboxyvinylpolymer neutralized as a gel-forming agent or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol and diethylene glycol monoethyl ether, and to the process for the preparation thereof Said formulations have advantages such as higher stability of the system and bioavailability of the active ingredient.
Claims11
Nimesulide topical formulations in the form of gel systems comprising carboxyvinylpolymer neutralized with aqueous solutions of weak bases or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol, diethylene glycol monoethyl ether and having a water content ranging from 40 to 95% by weight.
Formulations according to any of the above claims, further comprising additives selected from emollients, humectants, absorption enhancers, preservatives.
Dependencies are inferred from the claim text.