In-situ gel formation of pectin
AssigneeCarrington Laboratories, Inc.
InventorsYawei Ni, Kenneth M. Yates
Life of this patent
Estimating the term…
Abstract
In-situ gelation of a pectic substance. Composition, method of preparation, and method of use of a pectin in-situ gelling formulation for the delivery and sustained release of a physiologically active agent to the body of an animal. The pectin can be isolated from Aloe vera.
Claims75
A composition for the sustained release of a physiologically active agent in an animal, the composition comprising:
- the physiologically active agent;
- and
- a pectic substance in an amount effective to gel in situ in the animal.
A composition for the sustained release of a physiologically active agent in an animal, the composition comprising:
- the physiologically active agent;
- a carrier;
- a pectic substance in an amount effective to gel in situ in the animal.
A composition for the sustained release of a physiologically active agent in an animal, the composition comprising:
- the physiologically active agent;
- a carrier;
- an Aloe pectic substance in an amount effective to gel in situ in the animal.
A method for preparing a composition for the sustained release of a physiologically active agent in an animal, comprising:
- dissolving apectic substance in a carrier to give apectic solution or dispersion, wherein the amount of the pectic substance is effective to gel in situ in the animal;
- adding the physiologically active agent to the pectic solution or dispersion to give the composition.
A method for preparing a relatively dry composition for the sustained release of a physiologically active agent in an animal, comprising:
- dissolving a mixture of a pectic substance and a physiologically active agent in a carrier to give a solution of dispersion, wherein the amount of the pectic substance is effective to gel in situ in the animal;
- removing volatile components in the carrier to give the relatively dry composition.
A method for sustained releasing a physiologically active agent in an animal, comprising:
- dissolving a pectic substance in a carrier to give a pectic solution or dispersion, wherein the amount of the pectic substance is effective to gel in situ in the animal;
- adding the physiologically active agent to pectic solution or dispersion to give a composition;
- administering the composition to the animal.
Dependencies are inferred from the claim text.