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US 2002/0119930 A1Published application
Uses of lipopolysaccharide binding protein
AssigneeXoma Corporation
InventorsRussell L. Dedrick, Stephen F. Carroll
Life of this patent
Estimating the term…
Abstract
Novel LBP compositions and therapeutic uses for LBP are provided for preventing the adverse effects of exposure to endotoxin.
Claims4
A method for inhibiting adverse effects of endotoxin in circulation comprising the steps of
- determining the circulating lipopolysaccharide binding protein (LBP) level of a subject at risk for exposure to endotoxin, and
- administering to said subject having a circulating LBP level within the normal range an amount of LBP effective to elevate the circulating LBP level to inhibit the adverse effects of exposure to endotoxin.
A composition comprising lipopolysaccharide binding protein (LBP) in a solution buffered at about pH 7.5 and containing a poloxamer surfactant.
A composition comprising LBP in a solution buffered at about pH 7.5 and containing a poloxamer surfactant and a polysorbate surfactant.
Dependencies are inferred from the claim text.