Low fluorescence nylon/glass composites for micro-analytical diagnostic applications

A multi-cell substrate, useful for carrying a microarray of biological polymers comprising:

• a substantially non-reflective microporous membrane which provides little fluorescence from about three hundred (300) nm to about seven hundred (700) nm formed by a phase inversion process, the non-reflective microporous membrane comprising:
• a phase-inversion support;
• and
• a plurality of opaque solids that are substantially chemically non-reactive with the phase inversion support and intimately bound to, and/or partially/completely contained within, said phase-inversion;
• a non-porous substrate;
• and
• a surface treatment, operatively positioned between the substantially non-reflective microporous membrane and the non-porous substrate, for sufficiently covalently bonding the non-porous substrate to the microporous membrane wherein the combination multi-cell substrate produced thereby is useful in microarray applications.

A multi-cell substrate, useful for carrying a microarray of biological polymers comprising:

• an optically-passive substrate comprising:
• a phase-inversion support and opaque solids that are substantially non-reactive chemically with the phase inversion support, in a weight ratio with said phase-inversion support such that said optically-passive substrate absorbs light at substantially all wave lengths from about 300 nm to about 700 nm;
• a non-porous substrate;
• and
• a surface treatment, operatively positioned between the microporous membrane and the non-porous substrate, for sufficiently covalently bonding the non-porous substrate to the microporous membrane wherein the combination multi-cell substrate produced thereby is useful in microarray applications.