Texture masked particles containing an active ingredient
OwnerNarendra Parikh, Daniel McTeigue +2inventors
InventorsNarendra Parikh, Daniel McTeigue, David W. Wynn, Ravivaj S. Pillai
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Abstract
Texture masked particles and chewable tablets made therefrom are disclosed. The texture masked particles are comprised of a core containing an active ingredient, an optional first coating layer comprised of a taste masking agent that substantially covers the core; and a second coating layer, which optionally may substantially cover the first coating layer or the core, comprised of a film forming polymer and a anti-grit agent. The particles may be produced into a tablet form, such as a chewable tablet form, that provides for the immediate release of the active ingredient.
Claims72
A texture masked particle comprising
- a) a core containing an active ingredient;
- b) a first coating layer comprised of a taste masking agent that substantially covers the core;
- and
- c) a second coating layer on the surface of the first coating layer, the second coating layer comprised of
- i) a film forming polymer;
- and
- ii) an anti-grit agent.
A method of texture masking particles comprising an active ingredient, which comprises:
- a) applying a substantially continuous first coating layer over the particles, the first coating layer comprising a taste masking agent;
- and
- b) applying a second coating layer on the surface of the first coating layer, the second coating layer comprising a mixture of 1) a film forming polymer;
- and 2) an anti-grit agent.
A texture masked particle comprising:
- a) a core containing an active ingredient;
- and
- b) a texture masking coating layer on the surface of the core, the texture masking coating layer comprised of
- i) a film forming polymer;
- and
- ii) an anti-grit agent.
A method of texture masking particles comprising an active ingredient, which comprises:
- a) applying a coating layer over the active ingredient, the coating layer comprising a mixture of 1) a film forming polymer;
- and 2) an anti-grit agent.
A texture masked particle comprising a matrix, the matrix is comprised of:
- a) an active ingredient;
- b) a film forming polymer;
- and
- c) an anti-grit agent,
- wherein the film forming polymer and anti-grit agent are exposed at the surface of the particle in an amount effective for texture masking the active ingredient.
A method for making texture masked particles comprising an active ingredient, the method comprising spray-drying a mixture comprising
- a) a film forming polymer and an anti-grit agent, which together are present in an amount effective for texture masking the active ingredient;
- and
- b) the active ingredient.
Dependencies are inferred from the claim text.