Active substance patch, kind to the skin, for transdermal administration of nonsteroidal antirheumatics
AssigneeBeiersdorf AG
InventorsDetlev Radloff, Matthias Wasner
Life of this patent
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Abstract
An active substance matrix patch for controlled delivery of nonsteroidal antirheumatics to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitively adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and is composed of a) from 25 to 90% by weight of synthetic framework polymers based on polyisobutylene, b) from 5 to 40% by weight of amorphous poly-α-olefin, c) from 10 to 60% by weight of an insoluble hydrophilic filler having an average particle size of less than 100 μm, and d) from 0.001 to 20% by weight of a drug.
Claims9
An active substance matrix patch for controlled delivery of nonsteroidal antirheumatics to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitively adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and is composed of
- a) from 25 to 90% by weight of synthetic framework polymers based on polyisobutylene,
- b) from 5 to 40% by weight of amorphous poly-α-olefin,
- c) from 10 to 60% by weight of an insoluble hydrophilic filler having an average particle size of less than 100 μm, and
- d) from 0.001 to 20% by weight of a drug.
Dependencies are inferred from the claim text.