Mineral supplement
AssigneeKV Pharmaceutical Company
InventorsMarc S. Hermelin, George Paradissis, James A. Garegnani
Life of this patent
Estimating the term…
Abstract
The present invention is directed to a novel flavored extended release composition which forms a non-effervescent suspension when dropped into a liquid, and the methods of using said supplement, thereby minimizing and eliminating gastric discomfort. This flavored extended release composition provides the additional benefits of palatable taste and pleasant appearance.
Claims65
A composition for oral administration to an animal, which comprises:
- a plurality of extended release particles containing at least one biologically active substance, said particles being formulated in a solid dispersible tablet;
- a flavoring agent being formulated in the solid dispersible tablet;
- wherein the solid dispersible tablet forms a non-effervescent flavored suspension when placed in a liquid;
- and
- wherein the non-effervescent flavored suspension after being orally administered to the animal releases the biologically active substance over a period of about 2 hours to about 48 hours.
A composition for oral administration to an animal, which comprises:
- a plurality of extended release particles containing a biologically active substance;
- a flavoring agent being formulated in the extended release particles;
- wherein the plurality of extended release particles forms a non-effervescent flavored suspension when placed in a liquid;
- and
- wherein the non-effervescent flavored suspension after being orally administered to the animal releases the biologically active substance over a period from about 2 hours up to about 48 hours.
A composition for oral administration to an animal, which comprises:
- a plurality of extended release particles containing an alkaline salt of potassium, said particles being formulated in a solid dispersible tablet;
- a flavoring agent being formulated in the solid dispersible tablet;
- wherein the solid dispersible tablet forms a non-effervescent flavored suspension when placed in a liquid;
- and
- wherein the non-effervescent flavored suspension after being orally administered to the animal releases the alkaline salt of potassium over a period from about 2 hours up to about 48 hours.
A composition for oral administration to an animal, which comprises:
- a plurality of extended release particles containing at least one biologically active substance;
- a flavoring agent;
- wherein said particles and flavoring agent are contained in a capsule;
- and
- wherein a flavored suspension is formed when the capsule is opened and the contents distributed in a liquid or when the capsule is dropped into a liquid and said liquid stirred until the capsule dissolved.
A method of improving patient compliance with a therapeutic or nutritional regimen, which comprises:
- administering to an animal a non-effervescent flavored suspension formed by placing into a liquid a solid dispersible tablet comprising a flavoring agent and a plurality of particles containing a biologically active substance, said particles being coated with an extended release coating agent;
- wherein the non-effervescent flavored suspension after being orally administered to the animal releases the biologically active substance over a period of about 2 hours to about 48 hours.
A method of preparing an extended release composition for oral administration to an animal, which comprises:
- coating a plurality of particles of a biologically active substance with an extended release coating agent to form extended release particles;
- blending the extended release particles, a flavoring agent and at least one excipient to form a compressible mixture;
- and
- compressing the compressible mixture into solid dispersible tablets which form a non-effervescent flavored suspension when placed into a liquid.
A method of preparing a potassium chloride composition for oral administration to an animal, which comprises:
- coating a plurality of potassium chloride crystals with a coating agent to form extended release potassium chloride particles;
- and
- blending the extended release potassium chloride particles with a flavoring agent and at least one excipient to form extended release potassium chloride particles which form a non-effervescent flavored suspension when placed into a liquid.
Dependencies are inferred from the claim text.