Nitric oxide-releasing medical devices
AssigneeOffice of Technology Transfer, National Institutes of Health
InventorsLarry K. Keefer, Joseph A. Hrabie
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Abstract
A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N2O2− functional group; pharmaceutical compositions comprising the polymeric composition; and methods of treating biological disorders in which dosage with nitric oxide is therapeutic.
Claims38
A polymeric composition capable of releasing nitric oxide under physiological conditions, said composition comprising a biopolymer and a nitric oxide-releasing N2O2− functional group bound to said biopolymer.
Dependencies are inferred from the claim text.