Treatment of mucositis
AssigneeRxKinetix, Inc.
InventorsGary J. Rosenthal, Jeffrey B. Etter, Timothy C. Rodell, Wren H. Schauer, Adrian Samaniego
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Abstract
This present invention provides a therapeutic composition for use in the treatment of mucositis and a method for using such a therapeutic composition. The therapeutic composition includes a pharmaceutical substance effective for treating mucositis formulated with a biocompatible polymer, such as a biocompatible reverse-thermal gelation polymer.
Claims132
A therapeutic composition useful for treatment of a mucositis at a mucosal site, the composition comprising:
- at least one pharmaceutical substance, effective to provide therapeutic effect for at least one of the prevention of the mucositis and treatment of the mucositis;
- and
- at least one biocompatible polymer that is different than the pharmaceutical substance.
A therapeutic composition useful for treatment of mucositis at a mucosal site, the composition comprising a sulfur-containing antioxidant.
A method of delivering to a mucosal site within a host a pharmaceutical substance for treatment of mucositis at the mucosal site, the method comprising:
- introducing a therapeutic composition into the host, the therapeutic composition comprising the pharmaceutical substance and a biocompatible polymer, the pharmaceutical substance being effective for treating mucositis at the mucosal site;
- wherein, after the introducing, at least a portion of the biocompatible polymer and the pharmaceutical substance adhere to a mucosal surface at the mucosal site.
Dependencies are inferred from the claim text.